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When to Euthanize a Dog with Kidney Failure: 6 Signs It May Be Time

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Saying goodbye is never easy, but you don’t have to go through it alone.

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Dr. Lori Gibson of Compassionate Care
ABOUT THE AUTHOR

Lori Gibson, D.V.M.


Founder & CEO of Compassionate Care
Dr. Lori Gibson earned her undergraduate degree from the University of Portland before completing her Doctor of Veterinary Medicine at Oregon State University College of Veterinary Medicine in collaboration with Washington State University College of Veterinary Medicine. Recognizing the need for a compassionate, dedicated home euthanasia service, she founded Compassionate Care in 2009, providing in-home euthanasia to ensure pets experience comfort and dignity in their final moments. She later expanded her work by establishing the first Aquamation crematory in Portland, offering a sustainable alternative to traditional pet cremation.

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Deciding when to euthanize a dog with kidney failure is one of the most painful decisions a pet parent can face. As kidney disease progresses, it slowly takes away your dog’s energy, appetite, and comfort. While treatments can offer relief for a time, there may come a point when nothing seems to help, and the focus shifts from managing the disease to easing your dog’s final days.

This guide will walk you through the late stages of dog kidney failure, including the most common signs of decline, what treatment options can (and can’t) do, and how to assess your dog’s quality of life. Our goal is to help you make an informed, compassionate choice.

How Kidney Failure Changes Your Dog’s Daily Life

Chronic kidney disease (CKD), also known as renal failure, gradually impairs the kidneys’ ability to remove waste products and regulate hydration. In the early stages, you may notice your dog drinking water more frequently and needing to urinate more often as their kidneys work overtime to compensate.

As the condition progresses, toxins begin to accumulate in the bloodstream. This toxic buildup often leads to fatigue, reduced appetite, muscle loss, and general weakness. Dehydration becomes harder to manage, and your dog may show less interest in walks, food, or play. Over time, the decline in kidney function begins to affect every part of daily life.

As older dogs are more likely to develop kidney issues, regular blood tests become especially important for early detection and ongoing monitoring.

The Final Days of Kidney Failure in Dogs

The final stage of kidney failure often comes with subtle but unmistakable shifts. As chronic kidney disease reaches its final stage, your dog’s body may begin to shut down. The signs can be subtle at first but grow more persistent as the kidneys become less efficient which results in the buildup of toxins and dehydration.

Here are six common signs that suggest your dog may be approaching the end of life:

1. Your Dog Is Always Tired

Dogs with late-stage kidney failure often become noticeably weaker and much less active than usual. They often spend most of the day sleeping or lying down. They may seem too tired to respond to their name or get up for meals or walks. 

2. Loss of Appetite or Refusal to Eat

As kidney function declines, and toxic metabolites increase in the body, decreased appetite and nausea become common. Your dog may turn away from food, eat very little, or stop eating altogether. This leads to noticeable weight loss and further weakness.

In severe cases, kidney disease can also cause ulcers in the mouth or stomach, which contribute to discomfort and appetite loss.

3. Ongoing Nausea or Digestive Upset

If your dog drools excessively, licks their lips, or walks away from food, they may be feeling nauseated—one of the more distressing symptoms of kidney disease.  Consult with your veterinarian on ways to manage nausea and keep your dog eating and drinking as long as possible.  Proper hydration especially is critical for management of any sick pet.

If nausea no longer improves with medication, it can be a sign the disease is progressing past the point of management. In severe cases, kidney disease can also cause ulcers in the mouth or stomach, which contribute to discomfort and appetite loss.

4. Pale Gums and Unusual Breath Odor

You may notice a strong, unpleasant odor, often described as sour or ammonia-like bad breath. These are signs of dehydration and rising toxin levels, which are common in late-stage kidney failure.

5. Difficulty Standing or Walking

As muscle mass declines and energy fades, your dog may have trouble getting up, keeping balance, or walking without assistance. These physical changes make it harder for them to rest comfortably or move to food and water bowls.

6. Loss of Bladder Control

Frequent accidents, wet bedding, or incontinence may indicate that your dog is having trouble moving due to their feeling sick or otherwise being disinclined to move.  At this stage, your dog will require much more attention to maintain their cleanliness, comfort and dignity.

How to Assess Your Dog’s Quality of Life

Knowing whether it’s time to say goodbye is incredibly hard, especially when your dog has both good and bad days. That’s why many veterinarians recommend using a structured tool like the HHHHHMM Quality of Life Scale, developed by veterinary oncologist Dr. Alice Villalobos.

This method helps you evaluate your dog’s comfort and well-being across seven daily categories:

Hurt: Is your dog in pain despite medication? Do you see signs like panting, restlessness, or vocalizing?

Hunger: Are they still eating enough to maintain their energy, or refusing even favorite treats?

Hydration: Can they stay hydrated without assistance, or are they constantly dehydrated?

Hygiene: Are they able to stay clean and dry without intervention, or are they struggling with accidents and weakness?

Happiness: Do they still show interest in people, toys, or surroundings—or have they withdrawn?

Mobility: Can they get up, walk, and move comfortably, or are they relying on assistance?

More Good Days Than Bad: Are the good days outweighing the bad ones?

Each area is scored from 0 to 10. A total score above 35 suggests an acceptable quality of life. If several areas are consistently low, it may be time to consider end-of-life options.

Source: Villalobos, A. (2008). “The HHHHHMM Quality of Life Scale.” OVMA Conference Proceedings.

How to Know When It’s Time

There’s rarely a single moment when the “right time” feels perfectly clear. Most often, it’s a gradual shift – a buildup of signs that your dog is no longer comfortable or able to enjoy life the way they used to.

Even a single “rally” day can give hope, but it’s important to look at the overall pattern. If your dog can no longer consistently enjoy a high quality of life and daily routines have become a struggle, choosing euthanasia may be the most compassionate way to prevent further suffering.

Letting go doesn’t mean you’re giving up. It means you’re listening to what your dog needs most, and making a loving, selfless decision to protect their comfort in their final days.

Support, End-of-Life Care (Euthanasia) Options, and What Comes Next

When your dog is nearing the end of their journey, it’s important to know what choices are available and what to expect.

If treatments are no longer helping and your dog is showing signs of ongoing discomfort, euthanasia may be the kindest way to prevent further suffering. Many families choose to do this at home, where their dog can remain in a familiar, calm environment. Others prefer a veterinary clinic. Either option can be discussed with your DVM, family and/or veterinary care team.

Aftercare decisions are also deeply personal. Flame-based cremation and water-based cremation (Aquamation)are commonly chosen methods. If your dog received chemotherapy or other medications, home burial may not be safe or legally allowed in your area due to environmental concerns. It’s best to check local regulations and speak with a veterinary professional for guidance.

If you’re in the Portland, Oregon area, Compassionate Care offers 24/7 in-home euthanasia and aftercare services and can help answer any questions about what’s right for your situation.

Frequently Asked Questions

Can dogs recover from kidney failure?

Chronic kidney disease (or chronic kidney failure) (CKD) is progressive and incurable. While dogs don’t “recover,” many can live comfortably for extended periods with the right care. Early diagnosis, consistent treatment, and close monitoring can slow the progression and help maintain quality of life.

What treatments are available for dogs with kidney failure?

Supportive treatments can significantly ease symptoms and slow disease progression, especially when tailored into a personalized treatment plan created with your veterinarian. These may include:

  • Prescription renal diets that reduce kidney workload
  • Subcutaneous or IV fluids, also called fluid therapy, help combat dehydration and restore electrolyte balance
  • Omega-3 supplements such as fish oil may help reduce inflammation and slow kidney damage when used as part of a broader treatment plan.
  • Anti-nausea medications (e.g., Cerenia)
  • Blood pressure medication (e.g., amlodipine or enalapril) is used to manage high blood pressure, a common complication in dogs with kidney disease.
  • Phosphate binders to manage high phosphorus levels, potassium supplements
  • Medications for anemia if needed

Regular bloodwork and urine tests help your vet adjust treatments as the disease progresses.

Monitoring creatinine levels through blood tests helps evaluate how well the kidneys are functioning and guides adjustments to the treatment plan.

If your dog is experiencing acute kidney failure, prompt hospitalization, IV fluids, and intensive care may help stabilize their condition and restore some kidney function.

How long can a dog live with kidney failure?

It depends on the stage of the disease, the dog’s age and overall health, and how they respond to treatment.

  • Early to mid-stage CKD: Dogs may live 1–3 years with proper care.
  • Advanced-stage kidney failure: Life expectancy can range from a few weeks to several months.
  • Ultimately, life span varies greatly, which is why tracking quality of life and preparing for this difficult decision with your vet’s support is so important.

Is in-home euthanasia less stressful for dogs?

Yes. In-home euthanasia allows your dog to stay in a familiar, peaceful space, surrounded by loved ones. Many pet owners feel this helps reduce fear and anxiety during their dog’s final moments, creating a more gentle and meaningful goodbye.

Cremation for All Types of Pets

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